Stroke is a condition where there is loss of flow to parts of the brain, damaging brain tissue. Identifying strokes early-on could minimize deaths and resulting life-altering side effects. This research aimed to produce the first stroke predictive technology by monitoring homocysteine as a molecular biomarker. The colorimetric reaction was designed using Ellman's reagent to produce a yellow color and then quantified using minimized spectrophotometry by measuring light reflectance instead of light passage. The device, SpectroStroke, met engineering goals with 4.63% error when 10 to over 100 μmol/L concentrations. With development, SpectroStroke could make stroke monitoring feasible through one-step measurements.
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